蒺藜皂甙治疗冠心病心绞痛406例临床观察

作者	单位
王博文	吉林医学院心血管病研究室
马隆恩	吉林医学院心血管病研究室
刘同库	吉林医学院心血管病研究室
王玉杰	吉林医学院心血管病研究室
徐丽华	吉林医学院心血管病研究室
牟玉祥	吉林医学院心血管病研究室
纪文新	吉林医学院心血管病研究室
吴菊华	吉林医学院心血管病研究室
郭淑艳	吉林医学院心血管病研究室
杨先阶	吉林省造纸厂职工医院
郭金祥	吉林省造纸厂职工医院
林玉珍	吉林省造纸厂职工医院

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中文摘要:

本文报告了蒺藜皂甙治疗406例冠心病的临床观察结果,其改善心电图的总有效率为52.7%,显著高于对照组(35.8%);缓解心绞痛症状分级的总有效率82.0%,也高于对照组的67.2%(P<0.05)。说明蒺藜皂甙具有扩冠,改善冠脉循环作用,对缓解心绞痛、改善心肌缺血的心电图确有较好疗效。

英文摘要:

Coronary heart disease (CHD) was treated with saponin of Tribulus terrestris.According to 406 cases of clinical observation and a cross test (67 cases treated with Yufen Ningxin Pian(愈风宁心片) as control),the results showed that the total efficacious rate of remission angina pectoris was 82.3%. It was higher than the control group with a total effective rate of 67.2%(P<0.05).The total effective rate of ECG improvement (52.7%) was even higher than that of the control group (35.8%).It is shown that saponin of Tribulus terrestris has the action of dilating coronary artery and improving coronary circulation,and thus has better effects on improving ECG of myocardial ischemia.If taken for a long time,it has no adverse reaction on blood system and hepatic and renal functions.Neither does it have side effects.It is one of the ideal medicines to treat angina pectoris.

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