中西医结合治疗肝豆状核变性418例分析

作者	单位
杨任民	安徽中医学院附属医院
杨兴涛	安徽中医学院附属医院
鲍远程	安徽中医学院附属医院
韩咏竹	安徽中医学院附属医院
陈卫东	安徽中医学院附属医院
李圣业	安徽中医学院附属医院
蔡永亮	安徽中医学院附属医院
江停战	安徽中医学院附属医院

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中文摘要:

本文报告采用中药肝豆汤(片)及二巯基丁二钠(或二巯基丙醇)、青霉胺、葡萄糖酸锌(或硫酸锌)等中西药,治疗肝豆状核变性418例取得显著疗效。轻度组的显效率远高于中度及重度组(P<0.001),重度组的病死率显著高于轻度组(P<0.05)。肝豆状核变性型与假性硬化型的显效率显著高于腹型及肝脑型(P<0.01),前两组的病死率又显著低于后者。

英文摘要:

From 1974 to 1988,418 cases of Wilson’s disease were treated with TCM-WM in our hospital. 147 cases were of Wilson’s type;149 cases were of pseudosclerosis type;40 cases were of abdominal and hepatocerebral type;21 cases were of choreoathetosis type and 21 cases of other types.After a course of treatment for 3 to 6 months,103 patients showed marked improvement and 286 made some improvement,but no effect was found in 22 patients and 7 deaths were observed.The results were as follows:(1)The mortality in the severe and moderate groups were significantly higher than the mild(P<0.05)and the marked effective rate was less than the latter(P<0.01).(2)The marked effective rate was lower in abdominal and hepatocerebral type,and no signficant difference was found in recovery rate between Wilson’s type and pseudosclerosis type.

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