102例血栓闭塞性脉管炎患者体外血栓形成观察

对102例血栓闭塞性脉管炎患者和56例健康人测定体外血栓各值,并结合临床分期分级及中医辨证分型、中西医结合治疗等进行分析。结果:(1)患者组体外血栓各值均高于健康人(P<0.001)。(2)临床分期分级、中医分型不同,其体外血栓各值间有明显差别(P<0.05～0.001)。(3)中西医结合治疗前后体外血栓各值间存在显著差异(P<0.001)。表明体外血栓结果可反映临床病情变化,可作为临床分期分级、中医分型和判定疗效的客观参考指标。

英文摘要:

The formation of extrinsic blood thrombosis in 102 cases of thromboangiitis obliterans and 54 healthy persons were observed with chandler method and their clinical manifestations.All the 102 patients were male,of which 13 cases were in ischemic stage,45 cases in dystrophic stage,and 44 cases in necrotic stage.According to the differentiation of TCM,8 belong to Yin(阴)-cold type,50 belong to downward flowing of damp-heat type,42 belong to blood stasis type,and 2 others. Combining method of TCM-WM was adopted to give 45 cases systemic treatment,that is,taking the promotion of blood flow to remove its stasis as the dominant factor,accompanied by intravenous drip and operation.Results showed that the length,wet weight and dry weight of extrinsic blood thrombosis were higher apparently in the cases of thromboangiitis obliterans than those in healthy persons(P<0.001),and there were significant differences between the values of extrinsic blood thrombosis in different stages and different degrees.After systemic treatment with TCM-WM,the values of extrinsic blood thrombosis decreased remarkably,and their symptoms and signs improved or disappeared.The clinical total effective rate was 88.89%,and the decreasing rate of the values of extrinsic blood thrombosis was 98.9%.This suggested that the high blood coagulation and extrinisic thrombosis should draw special attention and may act as an approach reflecting the severity of the disease and evaluating the effects of treatment.

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