慢性肾炎患者外周血细胞化学ANAE变化与中医辨证关系的研究

运用细胞化学方法及显微分光光度技术对24例慢性肾炎患者和30例正常人进行外周血淋巴细胞及单核细胞的α-醋酸萘酯酶(ANAE)定性定量检测,结果正常人淋巴细胞阳性率为65.5±6.8%,其中点状颗粒型占53.6±6.7%,弥散颗粒型占11.9±3.4%,其单核细胞 ANAE 平均相对含量为54.78±3.34;肾阳虚组依次为39.7±7.4%、31.2±5.8%、8.5±2.7%及41.84±2.66;肾阴虚组依次为47.8±7.6%、42.4±6.3%、5.4±2.2%和51.26±2.59。经统计学处理,肾炎组与正常人、肾阴虚与肾阳虚之间差异均有不同程度的显著性意义,经中医辨证治疗后,各项指标均有一定程度的改善。并就慢性肾炎的中医辨证与 T 细胞亚群的关系作了讨论。

英文摘要:

The ANAE reaction of the peripheral blood from 24 patients of chronic glomerulonephritis (grouped according to the identification of TCM) and 30 normal individuals were observed by cytochemistry and microspectrophotometry.It was found that the percentages of positive lymphocytes of the deficiency of Kidney-Yin(阴)was 47.8±7.6%,among which the percentages of lymphocytes of spot granular pattern and scattered granular pattern were 42.4±6.3% and 5.4±2.2% respectively,the ANAE relative quality of monocytes of the deficiency of Kidney-Yin was 51.26±2. 59.They were 39.7±7.4%,31.2±5.8%,8.5±2.7% and 41.84±2.66 respectively in the deficiency of Kidney-Yang(阳).The results of normal group were 65.5±6.8%,53.6±6.7%,11.9±3.4% and 54.78± 3.34 in their given order.The differences in three groups each other were marked significantly.The authors have found the difference between the patients of chronic glomerulonephritis and the normal individuals was significant statistically.

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