140例胃部恶性肿瘤患者手术前后和死亡前血瘀证研究

作者	单位
周阿高	上海第二医科大学
丁钰熊	上海第二医科大学
陈梅芳	上海第二医科大学
黄大慰	上海仁济医院内科
李德华	上海仁济医院内科
江绍基	上海仁济医院内科

摘要点击次数: 1449

全文下载次数: 996

中文摘要:

三年多来,跟踪观察了140例胃部恶性胂瘤患者术前、术后和死亡前的舌质和5项血凝指标(AT-Ⅲ、Fn、Fa、ⅧR:Ag 和β-TG)。术前肿瘤患者紫舌阳性率高达58.0%,5项血凝指标测定值显著异常,说明胃部恶性肿瘤完全符合血瘀证诊断。术后紫舌阳性率和5项血凝指标均无显著好转,说明单纯手术切除没有根本改善肿瘤患者的血瘀状态。23例肿瘤患者在死亡前舌质与血凝指标显示了比术后、甚至术前更为明显的血瘀状态,说明血瘀证更是死亡前胃部恶性肿瘤的主要特征之一。提示:胃部恶性肿瘤与中医血瘀密切相关,血瘀证程度可作为判别病情轻重和预后的有效客观指标。

英文摘要:

In the past.three years,the authors observed substance of tongue and 5 indexes of blood coagulation(AT-Ⅲ,Fn,Fa,Ⅷ R:Ag and βTG)for a tong time in 140 patients of gastric malignant tumor pre-operation,one month post-operation and 3 months before death.All patients were verified as gastric carcinoma by pathological section.The results showed that the positive rate of substance of tongue in patients pre-operation was as high as 58%(51/88),5 indexes of blood coagulation in patients had obvious difference(P<0.001) comparing to that of healthy persons.This implied it existed relationship between gastric malignant tumor and blood stasis in TCM and accorded with diagnosis of blood stasis syndrome.With the resection of tumor focus,the states of blood stasis in patients had been improved to a certain extent.But the positive rate of substance of tongue post-operation was still as high as 51.1%(45/88) comparing to that pre-operation(P>0.05).5 indexes of blood coagulation in patients post-operation had no obvious improvement comparing to those pre-operation.This showed that the simple resection did not basically improve blood stasis in patients.The another important result was that the substance of tongue and 5 indexes of blood coagulation of 23 patients in last 3 months before death had more obvious blood-stasis comparing to those post-operarion even those pre-operation.This explained that blood stasis is one of the main characters of gastric malignant tumor before death.In conclusion,the extent of blood stasis syndrome can be used as an objective index to judge seriousness and prognosis of gastric malignant tumor patients’ condition.

关闭