| 胡锦心,贾广兴,阎志荣,贾慧荣,冯志达,那顺,纪方.参芍通冠片治疗冠心病心绞痛的临床及实验研究[J].中国中西医结合杂志,1990,(10):596-599,580 |
| 参芍通冠片治疗冠心病心绞痛的临床及实验研究 |
| Clinical and Experimental Study of Shenshao Tongguan Pian in Treating Angina Pectoris of CHD |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 冠心病 心绞痛 参芍通冠片 冠脉流量 血液流变性 血小板聚集 |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 1432 |
| 全文下载次数: 861 |
| 中文摘要: |
| 用中成药参芍通冠片采取随机双盲对照法,治疗冠心病心绞痛359例,心绞痛总有效率为94.71%,心电图改善率为63.38%,而丹七片对照组206例,心绞痛总有效率为66.99%,心电图改善率为23.38%。实验证明,该药有改善急性心肌缺血作用,能增加冠脉流量,降低心肌耗氧量,增加左心室排血量,降低血液粘稠度;对抗和减少血小板聚集性,抗缺氧、抗疲劳等功效。该药无毒副作用。是一种安全有效治疗冠心病心绞痛的新药。 |
| 英文摘要: |
| Shenshao Tongguan Pian (SSTGP) is composed chiefly of saponins from the stem and leaf of Ginseng and Radix Paeoniae Alba,etc.The authors applied this remedy for the treatment of angina pectoris of CHD.From 1982～1988,the authors carried out a randomized double blind trial on altogether 565 cases of CHD divided into an experimental group to be treated with SSTGP and a control group treated with another TCM proprietory medicine,Dan Qi Pian(丹七片),that had been used for many years clinically.The total effective rate of treating angina pectoris was 94.71% and ECG improvement rate 63.38% in experimental group whereas 66.99% and 23.38% respectively in the control group,the difference being very significant (P<0.01). Experiments with animals proved that SSTGP had more potent actions on CV system,such as dilatation of coronary arteries,promotion of coronary perfusion flow,lowering oxygen consumption of heart muscle,resisting the coronary spasm,anoxia and ischemia of heart muscle elicited by pituitrin,and prolongation of survival time of mice under anoxic state.In addition,laboratory examination also revealed SSTGP could promote the left ventricular output,lower the blood viscosity and inhibit the aggregation of blood platelets,Both acute and chronic toxicity tests showed SSTGP has no toxicity nor side effects,Therefore SSTGP is a new,safe and effective TCM proprietory remedy for CHD and angina pectoris. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息