桂枝汤对汗腺分泌作用的实验研究

作者	单位
富杭育	中国中医研究院中药研究所北京100700
贺玉琢	中国中医研究院中药研究所北京100700
李晓芹	中国中医研究院中药研究所北京100700
郭淑英	中国中医研究院中药研究所北京100700

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中文摘要:

采用动物后肢足跖部汗点着色试验,观察了相当于1/2、1和2倍临床等效剂量桂枝汤,在不同机能状态下,对汗腺分泌作用的影响。发现桂枝汤对正常大鼠有显著发汗作用;对汗腺分泌进行性受抑的流感病毒感染小鼠,有促进发汗、并使之趋向正常;对阿托品所致汗腺分泌抑制的造型大鼠,也能提高汗腺的分泌;对安痛定诱发汗腺分泌亢进的造型大鼠,能降低其发汗,使之恢复到正常水平。说明桂枝汤对汗腺分泌具有双相调节作用。

英文摘要:

Effects of the Decoction of Gui Zhi Tang(DGZT)on the hidropoiesis of animal paw in different pathophysiological conditions were studied with the examination of sweat stains.The diaphoresis was found in normal rats when 2.5～10.0 g crude drugs/kg p.o.of the DGZT was administrated.The diaphoretic function was also promoted by DGZT in mice infected with influenza virus which the function was gradually suppressed.The decoction had the action of bidirectional regulation and normalization in polyhidrosis induced by aminopyrines or in hypohidrosis induced by atropine on rats.

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