升血汤对肿瘤脾虚患者免疫功能的观察

作者	单位
饶燮卿	北京中医医院肿瘤科 (北京100010)
郁仁存	北京中医医院肿瘤科 (北京100010)
张建华	北京中医医院肿瘤科 (北京100010)
胡玉芳	北京中医医院肿瘤科 (北京100010)

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中文摘要:

通过对242例肿瘤脾虚病人免疫功能的观察,发现肿瘤脾虚患者的巨噬细胞吞噬活性、淋巴细胞转化率、NK 细胞的结合性和杀伤性、T 细胞亚群中的 T_H 细胞等免疫指标均明显低于正常人（P<0.002或 P<0.001）;患者的 C₃补体、血清免疫球蛋白以及 T 细胞亚群中的 Ts 细胞与正常人比较无明显差异,P>0.05。用升血汤治疗后,肿瘤脾虚患者的巨噬细胞吞噬率.淋巴细胞转化率、T 细胞亚群中的 T_H 细胞及 NK 细胞的杀伤性均有明显提高,P<0.001。上述结果提示:以健脾益肾中药组成的升血汤具有提高患者免疫功能的作用。

英文摘要:

242 cases of cancer patients with Spleen-deficiency syndrome have been studied. It has been found that some immune indexes such as phagocytic activities of macrophages,lymphocytic trans- formation rate,E-rosette forming rate,Th-cell in T cell subgroup,the NK cell cytotoxicity and combining ability,of cancer patients with Spleen-deficiency syndrome were lower than those of normal donor(P<0.001 or 0.002).After the patients were treated with Sheng Xue Tang (SXT),the immune indexes above mentioned have been increased significantly.These results suggest that SXT can improve the cell-mediated immune function, therefore,it can strengthen the anticancer ability of the patient,prolong the survival period of some patients.

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