张英华,刘玉兰,严述常.猪苓多糖对肝损伤小鼠单核巨噬细胞的影响[J].中国中西医结合杂志,1991,(4):225-226,198 |
猪苓多糖对肝损伤小鼠单核巨噬细胞的影响 |
Effect of Polyporus umbcllatus Polysaeeharide on Function of Macrophages in the Peritoneal Cavities of Mice with Liver Lesions |
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中文关键词: 猪苓多糖 肝损伤 腹腔单核巨噬细胞 |
英文关键词:Polyporus umbellatus polysaccharide liver lesions macrophages of peritoneal cavities |
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中文摘要: |
本实验抽取小鼠腹腔渗出细胞,体外培养,用荧光测定法检测腹腔巨噬细胞释放的 H2O2量。结果表明 CCl4所致肝损伤小鼠腹腔单核巨噬细胞数和释放 H2O2能力明显下降,猪苓多糖能增加和回升正常及肝损伤小鼠的腹腔巨噬细胞数量和释放 H2O2能力。该药能提高机体的细胞免疫功能,是治疗慢性肝炎的重要机理之一。 |
英文摘要: |
The cells in peritoneal cavities of mice were taken out and cultured in vitro.The amount to release H2O2,of the macrophages was assayed by fluorimetry.Polyporus umbellatus polysaccharide (PUP)could not only increase the number of macrophages and the amount of H2O2 release in the peritoneal cavities of normal mice.but also raise the lowered munber of macrophages and the ability to release H2O2 in the peritoneal cavities of the mice with liver lesions caused by CCl4significantly. So.PUP could improve the cellular immunity of normal mice and the mice with liver lesions. |
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