参茜固经冲剂治疗月经过多及其对血清、经血纤维蛋白裂解产物的影响

作者	单位
曹玲仙	上海医科大学妇产科医院上海 200011
俞瑾	上海医科大学妇产科医院上海 200011
夏惠琴	上海医科大学妇产科医院上海 200011

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中文摘要:

采用参茜固经冲剂治疗月经过多72例,并观察治疗前后经血及血清纤维蛋白裂解产物(FDP)含量。结果:72例中显效44例(61.1%),有效19例(26.4%),无效9例(12.5%),总有效率87.5%。经血中 FDP 含量治疗前后均高于血清中含量;治疗后经血及血清中 FDP 含量均较治疗前下降;显效病例经血 FDP 含量下降尤为明显。说明参茜固经冲剂是治疗月经过多的有效药物,其作用可能是参与纤溶系统,减少纤维蛋白裂解,增加纤维蛋白沉积,促使血管内膜闭合及凝血过程发生,达到固经摄血之目的。

英文摘要:

Shen-Qian Gu-Jing granule was used in the treatment of the menorrhagia in 72 cases including idopathic menorrhagia 28,uterine myoma 29,endometriosis 7,intrauterine device 5,postpartum and post induced abortion 3 cases.The amount of menstrual blood loss(MBL)and the fibrin degradation products(FDP)level in menstrual fluid and peripheral blood were measured before and after treatment.87.5% of all cases showed a significant decrease in MBL(P<0.05).The local FDP level significantly decreased parallel to effectiveness of MBL.The results suggested that the function of this Chinese herbs complex in menorrhagia was related to the regulation of FDP level.

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