麝雄灸线疗法治疗淋巴结结核39例及其免疫调控研究

作者	单位
洪淑云	同济医科大学附属协和医院中医科
黄坤堂	同济医科大学附属协和医院中医科
刘建国	同济医科大学附属协和医院中医科
王晓林	同济医科大学实验医学研究中心免疫室
苏娜	同济医科大学实验医学研究中心免疫室
朱慧芬	同济医科大学实验医学研究中心免疫室

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中文摘要:

本实验通过对经麝雄灸线疗法治疗前后39例淋巴结结核患者外周血细胞免疫功能及数目的检测,探讨淋巴结结核对麝雄灸线疗法的疗效及其免疫学机制。结果表明,患者外周血 CD₃⁺、CD₄⁺细胞百分率和 CD₄⁺/CD₈⁺比值均降低,与正常人组相比 P<0.001;B淋巴细胞增多和表达 DR 抗原的细胞亦增加;患者外周血单个核细胞对 PHA 刺激的应答明显低于正常（P<0.001）。经用此疗法治疗后,CD₃⁺、CD₄⁺和 CD₄⁺/CD₈⁺比值均上升（P<0.001）,淋转活性上升至正常;与此同时,症状改善,淋巴结肿大消失或明显缩小,溃疡愈合。论证了该疗法通过提高机体免疫力,促进疾病痊愈,是该疗法治疗淋巴结结核重要疗效机理之一。

英文摘要:

Immunological function and lymphocytic subsets of peripheral blood mononuclear cell （PBWC） from 39 patients with scrofula were investigated before and after treatment with musk-moxa-string therapy.The results.showed that the percentage of CD₃⁺,CD₄⁺ cells and the ratio of CD₄⁺/CD₈⁺ cells were markedly decreased in the patients than normal control （P<0.001）.On the contrary,the numbers of B lymphocytes and DR⁺ cells were increased.But the response of PBWC to phytohemag- glutin in（PHA）stimulation markedly decreased in the patients than the normal control.After treatment with musk-moxa-string therapy,the percentage of CD₃⁺,CD₄⁺ cells and the ratio of CD₄/ CD₈ were increased （P<0.001） and blastogenic response to mitogen stimulation with PHA-recovered to normal Meanwhile,the symptoms was improved and swell lymph node disappeared or was reduced markedly in size and the ulcer was healed completely.These findings suggest that the effect of musk-moxa-string therapy is caused by the enhancement of immunological capacity of the patients.

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