| 阎会君,马伟,王朝宏.康尔心1号治疗病毒性心肌炎临床及实验研究[J].中国中西医结合杂志,1991,(8):468-470,452 |
| 康尔心1号治疗病毒性心肌炎临床及实验研究 |
| Clinical and Experimental Study of the Effect of Kang Er Xin-Ⅰ on Viral Myocarditis |
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| DOI： |
| 中文关键词: 康尔心1号 病毒性心肌炎 左心功能 干扰素 NK 细胞 |
| 英文关键词:Kang Er Xin-I viral myocarditis left ventricular function virus Coxsackie B3 NK cell,interferon |
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| 中文摘要: |
| 观察康尔心1号对病毒性心肌炎患者左心功能影响并进行实验研究。结果表明:康尔心1号能使病毒性心肌炎患者主要左心功能指标明显改善,与辅酶 Q10治疗组比较有显著性差异。能体外直接灭活柯萨奇 B3病毒,并有效地保护培养小鼠心肌细胞免受柯萨奇 B3病毒的攻击;可促进病毒性心肌炎模型小鼠体内干扰素的诱生,提高 NK 细胞活性。 |
| 英文摘要: |
| Kang Er Xin-I（KEX-I）is a proved recipe used to treat viral myocarditis.It consists of Lonicera japonica.Opkiopogon iaponicus,Astragalus membranaceus mainly and possesses the effect of clearing away heat and toxic materials and supplementing the vital energy and nourishing.The clinical study was carried out with KEX-I according to a random,paired and cross-over design. Coenzyme Q10 was used as a control and left ventricular function was observed.The result showed: after being treated with KEX-I for two weeks,the 26 patients’ chief cardiac functional indexes assessed With STI improved markedly,the value of PEP/LVET and ICT/LVCT all decreased and the difference between the two groups was significant.The experimental study showed that KEX- I can inactivate directly the virus of Coxsackie B3,protect the heart cells in mice,prevent attack by Coxsackie B3,promote the growth of internal interferon and increase the NK cell’s function to regulate immunity in experimental mice. |
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