妊娠高血压综合征的预测和预防

作者	单位
钱祖淇	上海市南市区妇幼保健院上海 200010
刘翠芳	上海市南市区妇幼保健院上海 200010
陈益心	上海市南市区妇幼保健院上海 200010
郑红	上海市南市区妇幼保健院上海 200010
朱正廷	上海市南市区妇幼保健院上海 200010

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中文摘要:

本文研究表明,利用孕中期的平均动脉压(MAP-2)和中医辨证可预测妊娠高血压综合征(妊高征)的发生,MAP-2单项预测,其可靠率为50%左右,MAP-2≥12kPa且伴有肝肾阴虚者的妊高征发生机率为70%以上,说明妊高征的发生与孕中期的 MAP 和肝肾阴虚关系密切。对预测为阳性的424例孕妇给予预防性用药,其预防效果:中药优于西药,西药优于对照组,P 值均<0.005,服中药后妊高征的发生率由50%左右降至14.5%左右,效果显著,且可推迟妊高征的发病时间,对母婴均无副作用。

英文摘要:

Analysis of mean artery pressure (MAP-2) according to the differentiation of symptom complex of TCM can predict the occurrence of hypertension syndrome of pregnancy (HSP) at patients’ first visit to hospital during their middle gestational period (<24 pregnant weeks).424 pregnant women (MAP-2≥12kPa)were divided into 4 groups and given preventive treatment as follows:(1)The control group,122 women,no drugs were given;(2)the Theragan group,102 women;(3)the TCM (A) group, 100 women,those with Liver-Kidney deficiency of Yin(阴)or no apparent signs were given Qiju Dihuang Wan(枸菊地黄丸),and those with Spleen-Kidney deficiency of Yang(阳)were given Shenqiwan(肾气丸);(4)the TCM(B) group,100 women, were given Salvia miltiorrhiza plus (A) group’s drugs.The results of prediction:(1)The occurrence rate of HSP in the MAP-2<12kPa group was 10. 5%;in the MAP-2≥12kPa group,49.2%.The difference was significant.(2)The rate of deficiency of Yin in the MAP-2≥12kPa was significantly higher than in the MAP-2<12kPa.The rate of HSP in the deficiency of Yin was higher than in the nondeficiency of Yin.The rate of HSP increased to 70. 7% in the MAP-2≥12kPa with deficiency of Yin.The results of prevention:(1)The occurrence rates of HSP in 4 groups were 492%.30.4%,15% and 14% respectively.(2)There was no side effect for mother and infant after preventive treatment.No eclampsia occurred.

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