吕长兴,程炳权.枸杞多糖对Lewis肺癌放射增敏效应的研究[J].中国中西医结合杂志,1991,(10):611-612,582 |
枸杞多糖对Lewis肺癌放射增敏效应的研究 |
Radiosensitizing Effects of Lycium barbarum Polysaecharide for Lewis Lung Cancer |
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DOI: |
中文关键词: 构杞多糖 Lewis 肺癌 放射增敏 |
英文关键词:Lycium barbarum polysaccharide Lewis lung cancer radiosensitization |
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中文摘要: |
本实验使用 C57BL 纯系小鼠及可移植性 Lewis 肺癌模型,观察了枸杞多糖(LBP)对肿瘤的放射增敏效应。结果表明,单独使用 LBP 对肿瘤生长无明显抑制作用,而 LBP结合放疗显示出明显的放射增敏作用,得到剂量修饰因子平均为2.05。LBP 对急性乏氧肿瘤细胞也具有一定的放射增敏效应。本制剂对机体无明显的毒性作用。 |
英文摘要: |
The radiosensitizing effects of the Lycium barbarum polysaccharide(LBP)were observed by the model transplanted Lewis lung cancer on C57 BL mice.When LBP alone was administered,it was not obvious that LBP inhibited the growth of Lewis lung cancer.The significant radiosensitizing effects were obtained by combination of LBP and radiation.The mean numerical value of the dose modifying factors(DMF)was 2.05.The results also showed certain radiation enhancement effects of LBP to acute hypoxic cells of Lewis lung cancer.LBP presented few toxicity to the mice. |
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