| 许树强,武泽民,史载祥,马金莲,施雪筠,龙致贤,刘爱挛,杨树芳.参仙升脉液对实验性病态窦房结综合征的作用研究[J].中国中西医结合杂志,1991,(11):674-676,646 |
| 参仙升脉液对实验性病态窦房结综合征的作用研究 |
| Research on the Effect of Shen Xian Sheng Mai Ye(参仙升脉液)on Experimental Sick Sinus Syndrome |
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| DOI： |
| 中文关键词: 参仙升脉液 实验性病态窦房结综合征 心电图 心电生理指标 |
| 英文关键词:Shen Xian Sheng Mat Ye experimental sick sinus syndrome electrocardiogram cardioelectric physiologic index |
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| 摘要点击次数: 1243 |
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| 中文摘要: |
| 本研究用日本大耳白兔75只,平均分为5组,即参仙升脉液三个不同剂量组和阿托品、葡萄糖两个对照组。用20%甲醛外敷窦房结区造成病态窦房结综合征的动物模型,观察心率变化,心律失常情况和心电生理指标,结果表明参仙升脉液可以明显提高窦性心率,纠正心律失常以及改善窦房结功能。 |
| 英文摘要: |
| The effects of Shen Xian Sheng Mai Ye(SXSMY)on experimental sick sinus syndrome(SSS) were observed.By applying 20% formaldehyde to the rabbits’ sino-atrial node area,we got the acute animal model of SSS.By observing the rabbits’ heart rate(HR),arrhythmia and cardioelectric physiologic index in different periods,the results were as follows:(1)Increasing heart rate:SXSMY could increase rabbits’HR 10～30 times per minute by observing electrocardiogram within 2 hours (P<0.05～0.001).(2)Correcting arrhythmia:SXSMY could reduce arrhythmia of sinus nodal arrest and nodal rhythm remarkably.(3)Improving sinus atrial node function:SXSMY could improve sinus node recovery time (SNRT) and sinus atriaI conducting time (SACT) with the method of atrial pacing (AP) (P<0.01～0.001).But the above results did not appear in atropine and glucose groups. |
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