益肾宁治疗肾病激素撤退肾阳虚证的临床研究——附100例临床资料分析

Clinical Study of Yi Shen Ning(益肾宁)for Treating Deficiency of Kidney-Yang after Hormone Withdrawal of Primary Nephrotic Syndrome(PNS)——with the Clinical Analysis of 100 cases

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DOI：

中文关键词: 益肾宁肾病综合征激素撤退肾阳虚证

英文关键词:Yi Shen Ning Nephrotic syndrome hormone withdrawal deficiency syndrome of Kidney-Yang

基金项目:

作者	单位
洪用森	杭州红十字会医院
陶筱娟	杭州红十字会医院
秦卫星	杭州红十字会医院
王永钧	杭州市中医医院
徐琳	杭州市中医医院
朱彩凤	杭州市中医医院

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中文摘要:

本文报道100例原发性肾病综合征(PNS)患者在激素撤减至半量时加用温补肾阳的益肾宁口服液的临床效果。结果显示,此种中西医结合的分阶段投药方案,对PNS的激素撤退肾阳虚证候有明显疗效,不仅改善了症状,并能促使受外源性激素抑制的血皮质醇提前回升。使PNS的临床缓解率达68.57%,较单纯激素组为高(P<0.05)。尤其对原来激素依赖的患者,治后仍有58.3%的患者重新获得缓解。

英文摘要:

This paper reports that Yi Shen Ning which acts as warming and tonifying. Kidney-Yang was administrated on 100 cases of primary nephrotic syndrome (PNS) while adrenocortical hormone (ACTH) was diminished to half dosage. The results showed that to apply the integrated TCM and WM according to the different stage of PNS was quite effective to treat deficient syndrome of Kindey -Yang appeared after withdrawal of ACTH. This recipe not only could improve the symptoms, but also pick plasma cortisol up earlier than expected, which was inhibited by exogenous hormone.The total remission rate of YSN group was 68.75%, higher than that of ACTH group(P<0.05), especially for the cases dependent on exogenous hormone, the re-acquired remission.rate reached to 58.3%.

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