薛承锐,朱理玮,吴咸中.腹部外科血瘀证患者免疫功能状态的研究[J].中国中西医结合杂志,1992,(11):652-655,643 |
腹部外科血瘀证患者免疫功能状态的研究 |
Study of Immune Function Blood Stasis Syndrome in Patients with Abdominal Surgical Diseases |
免费下载全文 查看/发表评论 下载PDF阅读器 |
|
DOI: |
中文关键词: 腹部外科 血瘀证 T淋巴细胞亚群 免疫球蛋白 补体 T细胞超微结构 |
英文关键词:Blood Stasis Syndrome abdominal surgery ultrastructures of T cell immunoglobulins complements T lymphocyte subsets |
基金项目: |
|
摘要点击次数: 1084 |
全文下载次数: 898 |
中文摘要: |
应用流式细胞术测定53例不同类型的腹部外科血瘀证患者的外周血T淋巴细胞亚群,并应用免疫法检测血清免疫球蛋白和补体水平,观察部分患者的外周血T细胞超微结构。结果表明:气滞血瘀型患者的免疫功能正常;湿热血瘀型患者的细胞免疫和体液免疫的免疫应答活跃;气虚血瘀T?型患者细胞明显降低,T细胞显著升高,抗体水平亦降低明显,说明此型患者存在明显的细胞免疫及体液免疫功能抑制现象。电镜观察还发现气虚血瘀患者的T淋巴细胞有较明显的超微结构异常改变。 |
英文摘要: |
52 Patients with Blood Stasis Syndrome (BSS) in abdominal surgical diseases were divided into 3 types according to their symptoms, signs and natures of diseases. Peripheral blood T lymphocytesubsets of these BSS patients and 12 healthy persons were studied with Flow Cytometry andmonoclonal antibodies. The immunoglobulins and complements of these cases were also studied.There were no difference in T cell subsets, immunoglobulins and complemente between Qizhi(气滞)-BSS group and normal control. The Shire (湿热)-BSS group showed that CD8 cell, IgG, IgM, andC1, C3c were increased. These results showed that the immune response increased in this type of BSSpatients. In the Qixu (气虚)-BSS group, the CD3 was nearly normal, and the CD4+, CD4+/CD8+ ratio.and CD16+ were statistically decreased. However, the CD8+ cells markedly increased, the IgG, IgMand IgG were also lowered significantly in this type. The marked morphologic abnormal changes inultrastructures of T lymphocyte were found in 6 tients with Qixu-BSS group. These results showed that the Qixu type of Blood Stasis Syndrome patients were in the immuno-suppressive status. |
关闭 |
|
|
|