| 陈达仁,史荫绵,田桂琴,宫杰.川芎与阿斯匹林治疗短暂性脑缺血发作的临床研究[J].中国中西医结合杂志,1992,(11):672-674,645,646 |
| 川芎与阿斯匹林治疗短暂性脑缺血发作的临床研究 |
| Clinical and Experimental Study of Ligusticum Wallichii and Aspirin in the Treatment of Transient lschemic Attack |
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| DOI： |
| 中文关键词: 短暂性脑缺血发作 川芎 阿斯匹林 |
| 英文关键词:transient ischemic attack Ligusticum wallichii Aspirin |
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| 中文摘要: |
| 本文报告川芎与阿斯匹林治疗短暂性脑缺血发作158例,随机分川芎组111例,阿斯匹林组47例,随访观察1～2年。结果川芎组有效率89.8%,阿斯匹林组有效率61.7%,两组比较川芎疗效高于阿斯匹林(P<0.01),实验发现川芎有增加脑血流量、流速,扩张血管和降低外周动脉阻力作用,且其抑制血小板活性作用较阿斯匹林明显(P<0.05)。 |
| 英文摘要: |
| This paper reports the results of the treatment of 158 cases with transient ischemic attack （TIA）.They were randomly divided into Ligusticum wallichii group （111 cses） and Aspirin group （47 cases）.The results showed that the total effective rate in Ligusticum wallichii group and in Aspirin groupwere 89.2% and 61.7% respectively. The effect of former on the treatment of TIA was superior tolatter, and the difference between them was significant （P<0.O1）. Experimental study showed that Ligusticum wallichii has the effects of increasing-cerebral blood flow, accelerating the velocity ofblood flow, dilating the spastic artery and decreasing peripheral arterial resistance. Both of them hasthe functions of decreasing the levels of foromboxane B2 （TXB2）, β-thromboglobulin （β-TG） andplatelet factor IV （PF4） in plasma and increasing the concentration of 6-keto-prostaglandin F1α(6 keto-PGF1α) in plasma, the effect of Ligusticum wallichii was significantly better than Aspirin（P<0.05）. |
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