刘家祺,吴大文.中药配合化疗治疗32例术后成骨肉瘤的临床观察[J].中国中西医结合杂志,1993,(3):150-152,132 |
中药配合化疗治疗32例术后成骨肉瘤的临床观察 |
Clinical Observation on 32 Cases of Postoperative Osteogenic Sarcoma Treated by Chemotherapy Combined with Chinese Medicinal Herbs |
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中文关键词: 成骨肉瘤 化学疗法 中药疗法 |
英文关键词:osteogenic sarcoma side effect of chemotherapy Chinese herbal medicine treatment |
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中文摘要: |
本文报道中药配合化疗治疗32例术后成骨肉瘤的临床观察,并与26例对照组相比较。化疗分顺铂治疗及大剂量氨甲喋呤和长春新碱配合治疗两类。结果表明:对照组化疗的毒副反应和国内外文献报道基本一致;而中药组在全身和消化道反应以及骨髓抑制、心肝功能损害均较对照组明显减轻。两组比较差别有非常显著性意义。 |
英文摘要: |
32 cases of postoperative osteogenic sarcoma treated by chemotherapy combined with Chinese medicinal herbs were compared with 26 similar cases as control group. The drugs used in chemotherapy consisted of two regimens, DDP and high-dose MTX plus VCR. The results showed that the side effects of chemotherapy in control group were consistent with literatures; while the group treated with Chinese medicinal herbs suffered less toxic effects, the difference between two groups was statistically significant. The medicinal herbs used to reduce the side effects induced by DDP was Pinellia ternata, Amomum cardamomum, Bambusa textilis, Citrus reticulata etc.; while the herbs used to alleviate the adverse effects of high-dose MTX plus VCR was Gypsum, Anemarrhena asphodeloides, Rehmannia glutinosa, Ophiopogon japonicus, Scrophularia ningpoensis, etc. |
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