| 樊永平,聂惠民,周勇,严宣左,王庆国,傅延龄,陶君悌,张庆.健脾金丹对正常小鼠及环磷酰胺所致免疫受抑小鼠免疫功能的增强作用[J].中国中西医结合杂志,1993,(4):223-225,198 |
| 健脾金丹对正常小鼠及环磷酰胺所致免疫受抑小鼠免疫功能的增强作用 |
| Enhancing Effect of Jian Pi Jin Dan on Immune Functions of Normal and Cyclophosphamide Induced Immunosuppressed Mice |
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| DOI： |
| 中文关键词: 健脾金丹 胸腺指数 脾指数 淋巴细胞 血清溶菌酶 腹腔巨噬细胞 白细胞介素 |
| 英文关键词:Jian Pi Jin Dan spleen index thymus index lymphocyte serum lysozyme interleukin |
| 基金项目:国家教委博士点基金 |
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| 中文摘要: |
| 本实验对治疗小儿疳病良方健脾金丹的免疫调节作用进行初步研究,结果表明:本方对正常小鼠的血清溶菌酶含量,腹腔巨噬细胞吞噬能力,脾T、B细胞增殖,腹腔巨噬细胞产生白介素-1(IL-1)和脾T细胞产生白介素-2(IL-2)的能力均有显著的增强作用(有统计学意义),并对环磷酰胺(Cy)所致免疫受抑小鼠的上述指标及体重、胸腺指数和脾指数均有显著的恢复作用(有统计学意义)。说明本方有免疫增强作用,在组方上肝脾同调,符合小儿"脾常不足"、"肝常有余"的生理病理特点,固而有广阔的应用前景。 |
| 英文摘要: |
| By means of normal and cyclophosphamide(CY) injected NIH mice, the effect of Jian Pi Jin Danon immuno-modulation was studied which could treat the "Gan (疳)" disease effectively in TCM.Results: Markedly improved the level of serum lysozyme, enhance the phagocytosis of abdominalmacrophage. The proliferation of spleen T, B cells, the production of interleukin-1 (IL-1) bymacrophage and of interleukin-2 (IL-2) by T cells in normal and CY injected mice were alsoenhanced. Furthermore, it was able to restorce the weight, spleen and thymus index of CY injectedmice. This prescription can not only reinforce Spleen, but also regulate Liver, complying to thechildren’s physiological and pathological characteristics. |
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