健延龄对血清脂质和载脂蛋白及脂蛋白（a）水平的影响

作者	单位
陆德澄	镇江医学院附属医院
苏子杰	镇江医学院附属医院
芮涛	镇江医学院附属医院
载玉瑛	镇江医学院附属医院
隋风	镇江医学院附属医院
汤永祥	镇江医学院附属医院
张敬铭	江苏杨中县人民医院
汤国良	江苏工学院医院
吕圣荣	镇江丹凤医院
彭国民	江苏雷允上制药厂
阎荷珍	江苏雷允上制药厂

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中文摘要:

为了研究健延龄（含首乌、黄芪、西洋参等数种有效降脂中药）的调脂作用，将１２８例高脂血症患者分成治疗组及对照组进行随机双盲观察，３个月后健延龄组胆固醇（ＴＣ）、甘油三酯（ＴＧ）、胆固醇／高密度脂蛋白胆固醇（ＴＣ／ＨＤＬ－Ｃ）、载脂蛋白Ｂ（ＡｐｏＢ）、ＡｐｏＡ／ＡｐｏＢ、脂蛋白（ａ）〔Ｌｐ（ａ）〕与治疗前及与对照组比较，Ｐ均＜０．０１，认为该药有较好的调脂作用，有抗动脉粥样硬化作用，是值得推广应用的新药。

英文摘要:

Effect of Jian Yan Ling(JYL,mainly consisted of Succinum,Pteria margaritifers and Astragalus membranaceus etc.)on serum lipids was studied by double-blind method in 128 hyperlipemia patients.Patients were divided randomly into two groups,the test groups(64 cases)treated with JYL,while the other 64 cases treated with placebo as control for 3 months.Serum total cholesteral(TC),triglyceride (TG),TC-high density lipolipid-cholesterol(TC-HDL-C),apoproteins were observed before and after treatment.Results showed that the TC,TG,apoproteins and lipoprotein-a of test group were all dropped significantly after JYL treatment(P<0.01).The results suggested that JYL could regulate the blood lipids and could also exert an effect of antiatherosclerosis through reducing blood liprotein-a level.It is worth while to use JYL as an antihyperlipemic agent clinically.

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