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范亚平,蒋季杰,钱桐荪.慢性肾功能衰竭和血液透析患者脑干听觉诱发电位及“肾”与耳关系探讨[J].中国中西医结合杂志,1994,(4):220-221,197
慢性肾功能衰竭和血液透析患者脑干听觉诱发电位及“肾”与耳关系探讨
Significance of Brainstem Auditory Evoked Potential Determination in Chronic Renal Failure and Maintenance Hemodialysis Patients
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DOI:
中文关键词:  慢性肾功能衰竭  血液透析  脑干听觉诱发电位
英文关键词:chronic renal failure  hemodialysis  brainstem auditory evoked potentials
基金项目:
作者单位
范亚平 南通医学院附属医院肾病研究室 
蒋季杰 南通医学院附属医院肾病研究室 
钱桐荪 南通医学院附属医院肾病研究室 
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中文摘要:
      根据中医学“肾开窍于耳”的理论,我们分别测定了慢性肾功能衰竭(肾衰)和维持血液透析患者的脑干听觉诱发电位(BAEP)。20例慢性肾衰患者BAEP明显异常者13例,异常4例,主要表现为Ⅰ、Ⅲ、Ⅴ主波潜伏期(PLs)延长及Ⅰ-Ⅲ、Ⅰ-Ⅴ峰间潜伏期(IPLs)延长;8例平均血液透析4.2月者透析前后同体比较,透析后Ⅲ、ⅤPLs和Ⅰ-Ⅲ、Ⅰ-ⅤIPLs缩短有显著性意义。各PLs及IPLs与生化指标无显著相关性。BAEP测定及其动态观察为判断肾衰时内耳和听觉神经系统损害提供了客观指标,亦为中医“肾”与耳关系学说提供了电生理研究的佐证。
英文摘要:
      Brainstem auditory evoked potentials (BAEP) were measured in 20 chronic renal failure patients and 8 maintenance hemodialysis patients.The BAEP in chronic renal failure patients was showed that wave Ⅰ,Ⅲ,Ⅴ peak latencies(PL) and Ⅰ-Ⅲ,Ⅰ-Ⅴ interpeak latencies(IPL) were markedly increased..The significant reductions,although not to normal,of wave Ⅲ,Ⅴ PL and Ⅰ-Ⅲ,Ⅰ-Ⅴ IPLwere recorded in postdialysis(average 4.2 months) compared with that in predialysis.A correlation analysis revealed no consistent relationships between plasma proteins,hemoglobin,urea,creatinine serum electrolytes and BAEP PL or IPL.The authors realize that BAEP could be used as a subjective index in deciding the inner ear and nervous system damage in chronic renal failure,and it also provided an electrophysiologic evidence for the relationship of Kidney and ear in traditionalChinese medicine.
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