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金惠铭,焦东海.降脂减肥药对大鼠胃肠运动及腹壁脂肪细胞的影响[J].中国中西医结合杂志,1994,(4):230-231,198
降脂减肥药对大鼠胃肠运动及腹壁脂肪细胞的影响
Effect of Jiang-Zhi Jian-Fei Yao(降脂减肥药) on Gastro-Intestinal Movement and Adipose Cell of Abdominal Wall
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DOI:
中文关键词:  降脂减肥药  胃排空时间  脂肪细胞
英文关键词:Jiang-Zhi Jian-Fei Yao  body weight  stomach emptying time  intestinal movement  adipose cells
基金项目:
作者单位
金惠铭 上海医科大学病理生理学教研室 
焦东海 上海香山中医医院 
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中文摘要:
      降脂减肥药具有减肥的效果,其有效成分为精制大黄。给12只大鼠胃内注射降脂减肥药(每次0.25g/100g体重,每日2次),6天后发现与对照组比,用药组体重增加不明显(P>0.05),饲料摄入量减少,胃排空时间明显延长(P<0.05),肠内容物移动速度明显加快(P<0.05),腹壁脂肪细胞大小不匀,细胞内脂肪染色较浅,提示降脂减肥药的疗效与上述变化密切相关。
英文摘要:
      Jiang-Zhi Jian-Fei Yao (JZJFY),an obesity-reducing drug,its active principle is the refined Rhubarb,the mechanism of its obesity-reducing effect was studied.JZJFY was injected intragastrically.The results showed that there was no significant increased of body weight,but a reduction of food intake,prolongation of stomach evacuation time,acceleration of intestinal movement 6 days after medication in rats.Meanwhile the adipose cells in abdominal wall were varied in size,and with Sudan Ⅲ stain the color of adipose cells was light.Authors suggest that the obesity-reducing effect of JZJFY was relevant to above-mentioned changes.
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