中药配合环磷酰胺冲击治疗狼疮性肾炎41例疗效观察

作者	单位
阮劲	广东省番禺市人民医院
叶任高	中山医科大学肾脏研究所卫生部肾脏病重点实验室
梁萌	南京军区福州总医院

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中文摘要:

本研究着重对中药作为辅助治疗以提高西药疗效、减少不良反应及增加病情的稳定性进行探讨。我们以ＣＴＸ冲击疗法治疗４１例活动性狼疮性肾炎（ＬＮ），并在不同治疗阶段辨证使用中药，总有效率达９５．１％，结果提示ＬＮ以肝肾阴虚型居多，且证候可在不同的治疗阶段变化，适当辨证使用中药能扶正固本，促进骨髓造血，对抗ＣＴＸ等致免疫功能过度抑制，改善微循环及对恢复身体的自身稳定性有一定作用。

英文摘要:

41 active lupus nephritis patients were treated vigorously with cyclophosphamide (CTX),steroid used as routine,as well as TCM administed according to the various disease stage.35 cases administered with same western medicine but no TCM was taken as control group.Result:After a six-month treatment course,the therapeutical efficacy was significantly higher in treated group than that in control group (P<0.05).Lupus nephritis usually manifested itself as Liver-Kidney Yin deficiency in TCM.Our study suggested that Chinese herbs might play an important role in the treatment of lupus nephritis.

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