刘玉玺,王明正,孙美珍,牛淑贤,孙晓飞,李俊奎.狼毒大戟碱性提取液治疗癫痫72例临床分析[J].中国中西医结合杂志,1994,(5):282-284,261 |
狼毒大戟碱性提取液治疗癫痫72例临床分析 |
Clinical Analysis of 72 Epileptic Patients Treated with Alkaline Extract of Euphorbia Fisheriana |
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DOI: |
中文关键词: 狼毒大戟 癫痫 抗癫痫药 生物碱 |
英文关键词:Euphorbia fisheriana epilepsy anticonvulsant Euphorbia alkaloid |
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中文摘要: |
本文报告72例癫痫患者用狼毒大戟粗提的碱性液治疗后的临床效果,其中22例顽固性癫痫用单盲法与对照剂作了比较。结果狼毒大戟碱性液的总有效率为78%,显效率为42%,有效率为36%。治疗前后患者癫痫的发作次数有明显减少(P<0.05)。22例单盲治疗患者的有效率为59%,对照剂有效率为32%,二者比较亦有显著性差异(P<0.05)。狼毒大戟碱性液中的主要成分为狼毒生物碱,临床观察未见有明显毒副反应。认为该药药源广、价廉和有明显的抗癫痫作用。 |
英文摘要: |
The effect of 72 epileptic patients treated with alkaline extract of Euphorbia fisheriana (EF) was reported.22 of them with intractable epilepsy were compared with the treatment of both single-blind and placebo.The results showed that the total effective rate with EF was 78%,its marked effective rate was 42% and the effective rate 36%.The epileptic patients reduced their frequency of seizures significantly (P<0.05),while the effective rate of 22 epileptic patients with single-blind treatment was 59%,and that with placebo was 32%.There was a significant difference between the two groups (P<0.05).The active principle of Euphorbia fisheriana was Euphorbia alkaloid.There was no obvious adverse effect in clinical observation.It is considered that Euphorbia fisheriana is rich in resource,cheap,and with marked anticonvulsant effect. |
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