T细胞亚群测定与卵巢肿瘤辨证分型关系的研究

作者	单位
齐聪	上海中医药大学附属曙光医院妇科
庞泮池	上海医科大学肿瘤医院妇科
张志毅	上海中医药大学附属曙光医院妇科

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中文摘要:

本研究应用流式细胞仪和单克隆抗体技术测定了７３例卵巢肿瘤患者外周血Ｔ淋巴细胞亚群，试图阐明卵巢肿瘤患者各证型之间的免疫状况。结果显示：卵巢肿瘤患者外周血Ｔ细胞亚群变化与辩证分型有关，可作为临床判断虚证、实证及其免疫状况的敏感指标，为中医治疗卵巢肿瘤提供了客观依据。

英文摘要:

In order to study the difference in TCM types as well as between Deficiency and Excess type in immunity in the patients with ovarian tumors,the profile of peripheral blood T lymphocyte subsets in 73 cases of ovarian tumors was determined by using flow cytometry and monoclonal antibody technique. The results showed that the total T cells (OKT3) of peripheral blood were almost normal in 73 tumor cases. And 50 of them were malignant tumors in which T helper cell were progressively decreased and T suppresser cell gradually increased in accordance with the order of Qi-Deficiency,Yin-Deficiency, Qi-Yin Deficiency types. The T4/T8 ratio showed significant difference (P<0.01)compared with the control group and the initial ovarian tumor group. These results indicated that the change in the T lymphocyte subset in tumor was correlated with TCM type and this serves as both clinically sensitive indexes of different TCM type and reflection of the patient’s immunologic status.

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