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栾峰,殷鸿雁,董培英.脉络宁治疗妊娠高血压综合征46例临床观察[J].中国中西医结合杂志,1995,(3):153-155
脉络宁治疗妊娠高血压综合征46例临床观察
Observation on Treatment of Mailuoning Injection for 46 Pregnancy Induced Hypertension Patients
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DOI:
中文关键词:  脉络宁  硫酸镁  妊娠高血压综合征
英文关键词:Mailuoning Injection  magnesium sulfas  pregnancy induced hypertension
基金项目:
作者单位
栾峰 河南开封医学高等专科学校第一附属医院妇产科 
殷鸿雁 河南开封医学高等专科学校第一附属医院妇产科 
董培英 开封市第一人民医院妇产科 
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中文摘要:
      为了观察脉络宁治疗妊娠高血压综合征的效果,应用静脉滴注脉络宁治疗46例患者,并与应用硫酸镁治疗的40例作对照。结果:与治疗前比较脉络宁治疗组患者头痛、水肿症状均明显减轻(P<0.05),平均动脉压显著下降(P<0.05~0.01).血液流变学改善明显,红细胞压积的下降尤为显著(P<0.01)。尿蛋白改善、分娩方式、产后出血及新生儿Apgar评分与对照组比较均无明显差异。说明脉络宁治疗妊娠高血压综合征的主要机理是扩张血管、改善微循环的异常状态和血液流变性。
英文摘要:
      In order to observe the effect of treatment of Mailuoning Injection (MI) for pregnancy induced hypertension (PIH), 46 PIH patients in treated group were treated with intravenous dripping of MI and 40 patients in control group were treated with intravenous dripping of 25% magnesium sulfas.The result showed: The headache and edema ameliorated significantly in treated group in comparison with control (P<0. 05) . Both methods could decrease the levels of mean arterial pressure, but the former’s lowering arterial pressure was better than that of latter’s (P<0.05~0.01). The improvements of hemorheology in both groups after treatment were found, but the decrease of hematocrit was more significant in treated group (P< 0. 05) . No difference was found in albuminuria, delivery pattern, postpartum bleeding and neonatal Apgar Score between the two groups. The result suggested that the MI could prevent the progress of pathological process of the PIH,and relieve the systemic arteriolospasm, improve the microcirculation, change the hypercoagulability of the patients’blood and increase the blood flow in the patient of PIH.
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