复方丹参注射液治疗重症胰腺炎的临床研究

作者	单位
谢敏	南京市鼓楼医院
金遵禹	南京市鼓楼医院
叶耿辉	南京市鼓楼医院
周建新	南京市鼓楼医院
张凯	南京市鼓楼医院
仇毓东	南京市鼓楼医院

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中文摘要:

手术治疗重症胰腺炎后，应用复方丹参注射液治疗２８例，对照组１３例。结果表明：（１）两组并发症的发生率无明显差异，治疗组病死率３．６％，对照组病死率３０．８％，其差异显著（Ｐ＜０．０５）。（２）治疗组的红细胞压积从术前的４６．１±５．２％降低到３３．２±３．９％，其差异显著（Ｐ＜０．０５），而血小板和血红蛋白的变化无统计学意义。认为：复方丹参注射液能够改善重症胰腺炎的血液流变学异常，有助于胰腺组织的康复和成人呼吸窘迫综合征等严重并发症的纠正。

英文摘要:

Compound salviae miltiorrhizae injection was adiministered after operation for 28 cases of severe pancreatitis, and 13 cases were taken as a control group.The results showed that:(1) the difference was not obvious in the morbidity of complications between the two groups,but the mortality(3.6%) of the trial group was significantly lower than that(30.8%) of the control group(P<0.05);(2) Hematocrit was clearly decreased from 46.1±5.2% to 33.2±3.9% in the trial one (P<0.05), but platelet and hemoglobin showed no statistical significance.It is concluded that compound salviae miltiorrhizae injection might improve hemorheologic abnormalities of the disease, promote the recovery of the pancreatic tissue,and correct the serious complications such as adult respiratory distress syndrome etc.

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