| 房才龙,宗文九,范国荣,吕元文,王晓玲,周海中.肺癌患者辨证分型与外周血T淋巴细胞亚群和癌胚抗原的关系[J].中国中西医结合杂志,1995,(7):405-407 |
| 肺癌患者辨证分型与外周血T淋巴细胞亚群和癌胚抗原的关系 |
| Relationship between Syndrome Types of TCM in Lung Neoplasm Patients and Peripheral T Lymphocyte Subsets,Carcino-Embryonic Antigen |
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| DOI： |
| 中文关键词: 肺癌 辨证分型 T淋巴细胞亚群 癌胚抗原 |
| 英文关键词:lung neoplasm classification of Syndrome Differentiation T lymphocyte subsets,carcino-embryonic antigen |
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| 中文摘要: |
| 用直接葡萄球菌蛋白Ａ菌体花环法及放射免疫法检测了５６例肺癌患者外周血Ｔ淋巴细胞亚群及癌胚抗原（ＣＥＡ）值，并探讨其与中医证型间的关系。结果显示：肺癌患者ＯＫＴ３、ＯＫＴ４、ＯＫＴ４／ＯＫＴ８比值低于健康人（Ｐ＜０．０５～０．０１），ＯＫＴ８高于健康人（Ｐ＜０．０５），并依阴虚内热型、气滞血瘀型、痰湿阻肺型、气阴两虚型依次减低或增高；ＣＥＡ则以气滞血瘀型为最高，各证型间及与健康人比较均有显著性差异（Ｐ＜０．０１）。认为外周血Ｔ淋巴细胞亚群及ＣＥＡ可作为反映肺癌患者本虚及标实状况的参考指标，可为中医治疗肺癌提供客观依据。 |
| 英文摘要: |
| Fifty-six cases with lung carcinoma were detected for peripheral blood T lymphocyte by direct staphylococcal protein A(SPA) bacterial rose ring for carcino-embryonic antigen(CEA) by radioimmunoassay,and the relationship between T lymphocyte.CEA and Syndrome of TCM was explored.The results were as follows:the values of OKT3,OKT4,OKT4/OKT8 were lower in the lung carcinoma than that in healthy subjects(P<0.05～0.01),but OKT8 was higher(P<0.05);The values of T lymphocyte lowered or increased in the order of Yin Deficiency with internal Heat,Qi Stagnation with blood stasis,Phlegm-Dampness in Lung,Qi-Yin Deficiency,but that of CEA was the highest in Qi-stagnation with blood stasis.There was a significant difference between all Syndrome-types of TCM and the healthy subjects(P<0.01).Therefore,it is suggested that the values of peripheral T lymphocytes and CEA with the lung carcinoma were regarded as good referential parameters in reflection the condition of Deficiency in Vitality and Excess in Superficiality,which offered the objective evidence for the TCM treatment. |
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