理气活血开闭固脱法治疗感染性休克的研究

作者	单位
金妙文	南京中医药大学
周仲瑛	南京中医药大学
张世玮	南京中医药大学
朱荃	南京中医药大学
周树云	南京中医药大学
周学平	南京中医药大学
王志英	南京中医药大学
黄泉秀	南京中医药大学
吴勉华	南京中医药大学
何亚维	南京中医药大学

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中文摘要:

针对感染性休克气滞血瘀、正虚欲脱的病理特点，以理气活血、开闭固脱为基本治法，辨证研制成治疗本病的系列中药新制剂（包括抗厥通脉注射液、益气救阴注射液、益气回阳注射液）共治疗感染性休克１８３例，无效率为４．３７％，与对照组（２３．０％）比较，有显著性差异（Ｐ＜０．０１）。实验研究表明，上述药物均有迅速升高血压效应，稳压时间长，能增加肾血流量，降低血液粘度和实验动物主要脏器脂质过氧化物含量，稳定生物膜，保护细胞功能。

英文摘要:

Based on the pathogenesis of infectious shock which were stagnation of Qi, blood stasis,impairment of body resistance and trends to collapse, a series of new preparations of Traditional Chinese Medicine was developed, Injection Kangjue Tongmai, Injection Yiqi Jiuyin and Injection Yiqi Huiyang, which could Liqi Huoxue and Kaibi Gutuo(regulate the flow of Qi, promote blood circulation, strengthen the body resistance and remit collapse), the result of 183 cases of infectious shock treated with them showed that the mortality was 4.37%,significantly lower than that of control group(23.0%). All three injections could rapidly elevate blood pressure and stabilize it for prolonged time, increase renal blood flow and lower blood viscosity. In animal experiment, the injections reduced lipid peroxide of vital organs, stabilized bio-membrane, protected the cell structure and maintained their normal functions.

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