梁民里道,吕联煌,张学敏,欧海云.增龄对血瘀证及血浆血栓素B2和6-酮-前列腺素F1α水平的影响[J].中国中西医结合杂志,1995,(11):652-654 |
增龄对血瘀证及血浆血栓素B2和6-酮-前列腺素F1α水平的影响 |
Effect of Age on Hemostasis and Plasma Level of TXB2 and 6-keto-PGF1α |
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DOI: |
中文关键词: 增龄 血瘀证 血栓素B2 6-酮-前列腺素F1α |
英文关键词:hemostasis TXB2 6-keto-PGF1α age |
基金项目:福建中医药中西医结合科研基金 |
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中文摘要: |
对134例20岁以上健康人进行了血瘀证的调查,发现45.52%的健康人群表现血瘀征候,随着增龄血瘀征候检出率呈递增变化。采用放射免疫分析法检测血栓素B2(TXB2)、6-酮-前列腺素F1a(6-keto-PGF1α)及T/K比值。结果显示:中年及老年组TXB2水平均明显高于青年人(P均<0.01)。而6-keto-PGF1αv水平各年龄组变化不大,T/K比值老年人显著高于青年人(P<0.01)。表明随着年龄增长,血液逐渐呈现高凝倾向,并与上述指标相关。这对防治心脑血管疾病,防治中医血瘀证具有重要的理论意义和实际意义。 |
英文摘要: |
Hemostasis(HS) in 134 healthy subjects of over 20 years old was investigated.The cases with HS symptom were 45.5%,which increased with age.TXB 2,6-keto-PGF1aαand T/K ratio were measured by radioimmuno assay(RIA).Results:elevation of TXB2 was more significant in the middle age and old age than in the young group(P<0.01).But the level of 6-keto-PGF 1αin various age group didn’t changed significantly:while the ratio between TXB2and 6keto-PGF1α was more significant in the aged than in the young person(p<0.01).The results revealed that there was hypercoagulable tendency with the increase of age,and it was correlated with TXB 2 and 6-keto-PGF 1α.It is significant in theory and practice to prevent and cure the cardiovascular and cerebrovascular disease as well as HS with the traditional Chinese medicine. |
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