肾虚证与骨密度的关系

作者	单位
郭素华	华西医科大学第一附属医院
李洪成	成都市第一人民医院
邹才华	华西医科大学第一附属医院
许志奇	华西医科大学第一附属医院
杨定焯	华西医科大学第四附属医院
林如平	成都市第一人民医院
雷韵修	成都市第一人民医院
高军	成都市第一人民医院
吴凯	成都市第一人民医院
孙孝洪	华西医科大学第一附属医院
许永春	四川省干部疗养院
迟焕海	华西医科大学第一附属医院

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中文摘要:

选择４０～６９岁的受试者２０６８例进行了骨密度测试。其中肾虚证１１４４例，男３２０例，女８２４例；无肾虚证６０８例，男３０６例，女３０２例；肺虚证１６４例，男８０例，女８４例；脾虚证１５２例，男７６例，女７６例。研究发现，按同性别、同年龄比较，肾虚证骨密度明显低于正常值和无肾虚证受试者，也区别于肺虚证、脾虚证受试者。说明肾虚证有骨密度的相应变化，印证了中医＂肾主骨＂的经典理论。还提出将４０～４９岁年龄组骨密度的正常值减去２倍标准差的低限，作为判别肾虚证的临界值，即男性骨密度＜０．６ｇ／ｃｍ２，女性骨密度＜０．５ｇ／ｃｍ２，经临床反馈验证，男性相关符合率为７６％，女性相关符合率为８０％，因此认为该临界值在排除其它影响因素以后，可作为肾虚证的客观参考指标之一。

英文摘要:

In order to study the relationship between Kidney Deficiency Syndrome(KDS) and bone density(BD),the BD of 2068 subjects(40～69 years old) was measured with SPA-IIC type monophoton BD scanning device made in China.The subjects including 1144 cases of KDS(320 males and 824 females);608 cases without KDS(306 males and 302 females);164 cases of Lung Deficiency(80 males and 84 females);152 cases of Spleen Deficiency(76 males and 76 females).Through comparison with the same sex and age group.it was found that BD in KDS patients was significantly lower than that in the normal subjects and those without KDS,also lower than that in the Lung and Spleen Deficiency patients.It indicated that KDS had the corresponding BD changes,which confirmed the TCM classical theory"The Kidney governs the bone".Based on the measuring data,the authors took the lower limit of BD normal value minus two folds of SD as the critical value for KDS diagnosis in 40～49 years age group,i.e.,male BD<0.6 g/cm 2,female BD<0.5g/cm 2.The clinical feedback showed that the male and female related coincident rates were 76% and 80% respectively.Therefore ,the critical value could be taken as an objective index for KDS diagnosis after excluding other affecting factors.

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