中药治疗减少腹膜透析次数的临床观察

本研究试图用中药配合腹膜透析治疗，以在改善肾功能的同时减少腹膜透析次数。结果表明：透析３个月后，中药组血清ＢＵＮ、Ｃｒ和平均动脉压（ＭＡＰ）值比透析１个月时有明显降低（Ｐ＜０．０１），Ｈｂ有明显升高（Ｐ＜０．０１）；血清ＢＵＮ、Ｃｒ和ＭＡＰ值与减少透析组相比有明显降低（Ｐ＜０．０１，Ｐ＜０．０５），Ｈｂ有明显升高（Ｐ＜０．０５），而上述四项指标与正常透析组相比，无明显差异（Ｐ＞０．０５）；中药组疗效及水肿消退率明显优于减少透析组（Ｐ＜０．０１），而与正常透析组之间无显著性差异（Ｐ＞０．０５）。提示：用中药配合腹膜透析治疗可适当减少需长期行腹膜透析尿毒症患者的腹膜透析次数。

英文摘要:

Traditional Chinese herbal medicine was used in combination with peritoneal dialysis(PD)in order to improve the renal function and reduce the frequency of PD.The results indicated that,after 3 months of PD+ TCM,the serum BUN,creatinine and mean arterial pressure of therapeutic group lowered and the hemoglobin elevated as compared with those after 1 month of PD(P<0.01),the difference of above-mentioned criteria between PD+TCM group and less frequent PD(LEPD)group was significant too,while there was no obvious difference in comparison of the PD+TCM group with regular PD group(P>0.05).The effective rate and the edema cure rate of TCM+PD group were superior to the LFPD group,but had no evident difference as compared with the regular PD group.The results revealed that PD combined with TCM treatment might reduce the frequency of PD for the uremia patient deserved long-term PD therapy.

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