| 郑丽丽,阎西艴,张永珍,韩萍,叶启霞,江戎,申红.赤芍对高脂兔血小板胞浆游离钙、红细胞膜Ca2＋－Mg2＋－ATP酶活性的影响[J].中国中西医结合杂志,1996,(5):295-296 |
| 赤芍对高脂兔血小板胞浆游离钙、红细胞膜Ca2＋－Mg2＋－ATP酶活性的影响 |
| Effect of Paeonia lactiflora on Platelet Cytosolic Free Calcium and Erythrocyte Membrane Ca￣(2+)-Mg￣(2+)-ATPase Activity in Hyperlipid Rabbits |
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| DOI： |
| 中文关键词: 赤芍 游离钙 红细胞 血小板 钙－镁－ATP酶 |
| 英文关键词:Paeonia lactiflora free calcium erythrocyte platelet Ca￣(2+)-Mg￣(2+)-ATPase |
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| 摘要点击次数: 1544 |
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| 中文摘要: |
| 本研究观察了赤芍对高脂兔血小板胞浆游离钙（［Ｃａ２＋］ｉ）、红细胞膜钙－镁－ＡＴＰ酶（Ｃａ２＋－Ｍｇ２＋－ＡＴＰａｓｅ）活性血清钙及血脂的影响。结果表明：血小板［Ｃａ２＋］ｉ含量赤芍组（２７６．２５±２７．００ｎｍｏｌ／Ｌ）显著低于高脂组（３９０．８８±７０．００ｎｍｏｌ／Ｌ），Ｐ＜０．０１；红细胞膜Ｃａ２＋－Ｍｇ２＋－ＡＴＰａｓｅ基础及激活活性（μｍｏｌ·ｐｉ－１·ｍｇ－１·ｈ－１）赤芍组（０．７９±０．０５，１．３４±０．１０）明显高于高脂组（０．６５±０．０９，１．０４±０．１３），Ｐ＜０．０１。说明赤芍可提高高脂血症兔红细胞Ｃａ２＋－Ｍｇ２＋－ＡＴＰ酶基础及激活活性。 |
| 英文摘要: |
| The effect of Paeonia lactiflora(PL) on platelet cytosolic free calcium and erythrocyte membrane Ca2+-Mg2+-ATPase activity in hyperlipid rabbits were observed. Results showed the level of platelet cytosolic free calcium in the PL group(276.25±27.00nmol/L) was significantly lower than that in the cholesterol group(390.88±70.00nmol/L), P<0.01, the basal and calmodulin-stimulated activities of erythocyte membrane Ca2+-Mg2+-ATPase in PL group (0.79±0.05 μmol· pi-1·mg-1·h-1 and 1 .34±0.10μmol· pi-1·mg-1·h-1) were higher than that in the cholesterol group (0.65±0.09μmol·pi-1·mg-1·h-1 and 1.04±0.13μmol·pi-1·mg-1·h-1). |
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