| 赵江云,宋卫东,刘中本,吴华强,张安成,庞玉英,刘丽华.支气管肺灌洗液中SOD和LPO与肺气虚证的关系[J].中国中西医结合杂志,1996,(7):405-407 |
| 支气管肺灌洗液中SOD和LPO与肺气虚证的关系 |
| Relationship between Lipid Peroxidase and Superoxide Dismutase in Bronchoalveolar Lavage Fluid and Pulmonary Qi Deficiency Syndrome |
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| DOI： |
| 中文关键词: 肺气虚证 支气管肺灌洗液 过氧化脂质 超氧化物歧化酶 |
| 英文关键词:Pulmonary Qi Deficiency Syndrome bronchoalveolar lavage fluid superoxide dismutase lipid peroxidase |
| 基金项目:国家自然科学基金,国家中医药管理局资助 |
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| 中文摘要: |
| 检测４０例慢性支气管炎肺气虚证患者及３６名健康人外周血、支气管肺灌洗液（ＢＡＬＦ）中超氧化物歧化酶（ＳＯＤ）、过氧化脂质（ＬＰＯ）以及肺泡巨噬细胞（ＡＭ）内ＳＯＤ含量。结果表明：（１）肺气虚证患者外周血ＳＯＤ、ＬＰＯ与健康对照组无明显差异。（２）肺气虚证患者ＢＡＬＦ中ＬＰＯ明显升高，而ＳＯＤ明显下降。（３）相关分析发现，ＢＡＬＦ中ＳＯＤ主要与ＡＭ数量相关，而ＬＰＯ主要与中性粒细胞数量相关。ＢＡＬＦ中ＳＯＤ和ＬＰＯ是评价肺气虚证的指标之一。 |
| 英文摘要: |
| Investigating the levels of lipid peroxidase(LPO) and superoxide dismutase(SOD) in serum,bronchoalveolar lavage fluid(BALF) and alveolar macrophage(AM) were determined in 40 chronic bronchitis patients with Pulmonary Qi Deficiency(PQD) Syndrome and 36 normal subjects.Results showed:(1) No significant differences were found between PQD syndrome and normal subjects on serum SOD or LPO levels.(2)Patients with PQD Syndrome,LPO level in BALF was significantly higher,and SOD significantly lower, when compared with normal subjects.(3)Through correlation analysis,it was found in BALF that SOD level was markedly correlated with AM,while LPO was significantly correlated with neutrophil.In short,SOD and LPO in BALF play an important role in the development of the PQD Syndrome,and are good indications in evaluating the PQD Syndrome. |
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