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王树庆,李建华,张圣明,刘捷,李义清,胡匡祜,李子孝,谭爱美,黄宗滨.补肾化瘀方药对再生障碍性贫血患者骨髓细胞DNA含量的影响[J].中国中西医结合杂志,1996,(7):411-413
补肾化瘀方药对再生障碍性贫血患者骨髓细胞DNA含量的影响
Effect of Bushen Huayu Recipe on DNA Content of Myeloid Cells in Aplastic Anemia Patients
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DOI:
中文关键词:  补肾化瘀方药  再生障碍性贫血  计算机图像分析技术
英文关键词:Bushen Huayu recipe  aplastic anemia  computer image analysis technique
基金项目:北京中关村地区联合分析测试中心资助
作者单位
王树庆  
李建华  
张圣明  
刘捷  
李义清  
胡匡祜  
李子孝  
谭爱美  
黄宗滨  
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中文摘要:
      采用计算机图像分析技术,对30例再生障碍性贫血(AA)患者经补肾化瘀方药治疗前后的骨髓有核细胞进行DNA含量测试分析,并与30例健康人的测试结果比较,结果表明:AA患者治疗前骨髓有核细胞DNA平均含量明显低于健康人(P<0.01),治疗后与健康人趋于同一水平。补肾化瘀方药影响DNA含量的机理可能与改善骨髓微循环或(和)刺激造血细胞从而促进DNA合成代谢有关。
英文摘要:
      Quantification of myeloid cell-DNA in 30 cases with aplastic anemia(AA) was performed with computer image analysis techniquee pre-and post-treatmentally with Bushen Huayu recipe respectively,and compared with that of a control group of 30 healthy subjects.The results showed the average level of DNA in myeloid cells from AA patients was significantly lower than that of control(P<0.01)prior to the treatment and it raised to the same level approximately as that of control after the treatment.This change of DNA quantity might result from the improvement of microcirculation or(and) stimulus to hematopoietical cells which accelerated the DNA anabolism in these cells.
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