红景天胶囊对心肌缺氧、缺血保护作用的实验研究

本研究观察到，灌胃给红景天胶囊可使小鼠夹闭气管后心电消失时间、常压和低压缺氧条件下平均存活时间延长，使大鼠注射垂体后叶素所致心肌缺血阳性反应数减少；大、中两剂量组与生理盐水对照组比较，各项指标均有显著性差异（Ｐ＜０．０１或＜０．０５），其作用强度亦优于复方丹参片对照组。表明本品对心肌缺氧缺血具有保护作用。本研究还评价了红景天胶囊益气化瘀的效应，认为本品的以上作用可能与其益气化瘀功效有关。

英文摘要:

Effect of Rhodiala capsule on the disappearance time of electrocardiographic sign caused by clamping the trachea,the mean survival time of hypoxia under ordinary or low pressure and the positive reaction of myocardial ischemia induced by injecting pituitrin in mice were observed. Results showed Rhodiala of various dosage perfused by gastric tube could prolong the former two parameters and reduce the number of the latter, as compared with control group treated with normal saline, the differences were significant (P <0.01 or m-0.05j, and the effect of Rhodiala was more potent than that of compound Salviae tablet. It suggested that Rhodiala capsule has protecting action on myocardial anoxia and ischemia. The supplementing Qi and resolving blood stasis effects of Rhodiala were also evaluated in this article and the relationship of above-mentioned actions of Rhodiala was discussed.

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