林文森,石志兴,马恩明,陈洁,伍孝先,周文洛,袁洪达.补肾聪耳片治疗感音神经性耳聋的临床和实验研究[J].中国中西医结合杂志,1996,(11):658-660 |
补肾聪耳片治疗感音神经性耳聋的临床和实验研究 |
Clinical and Experimental Study on Bushen Cong-er Tablet in Treating Sensorineural Hearing Loss |
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DOI: |
中文关键词: 补肾聪耳片 感音神经性耳聋 中毒性耳聋动物模型 |
英文关键词:Bushen Cong-er tablet sensorineural hearing loss toxic deafness model |
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中文摘要: |
根据中医有关“肾主耳”的论述,采用补肾活血通窍为主的纯中药制剂补肾聪耳片对310例感音神经性耳聋治疗观察,结果总有效率为71.9%。动物实验亦证实本药能防治氨基糖甙类抗生素所致的药物性中毒性耳聋,能调整耳蜗组织的环核苷酸含量,提高耳蜗组织的SOD含量和降低LPO含量。 |
英文摘要: |
According to the"Kidney has its orfice in the ear"in TCM theory,the authors adopted Bushen Cong-er tablet,a TCM preparation with the treating principles of the Kidney reinforcing and blood circulation promoting to remove stasis as well as to open up the apertures in treating 310 cases of sensorineural hearing loss.The results showed that therapeutical effect was satisfactory.The total effectve rate was 71.9%. Animal experiment also demonstrate the durg could prevent and cure the aminoglycoside antibiotic ototoxic hearing loss, could adjust the cochlear cyclic neucleotides as well as its SOD level and reduce the LPO level,raise the thyroid function and the function of sexual gland. |
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