足三里穴位免疫疗法防治过敏性哮喘临床及实验研究

用足三里穴位免疫疗法对过敏性哮喘进行防治研究。临床观察６９例患者，结果：足三里穴位免疫组不仅临床疗效明显高于常规脱敏对照组，且能明显降低患者血清总ＩｇＥ值，促进特异性抗尘螨ＩｇＥ转阴，使ＳＩｇＡ值升高，嗜酸性粒细胞绝对值下降，肺功能恢复。动物实验结果显示，穴位免疫疗法较单纯脱敏组和生理盐水组更有效地延长豚鼠过敏性哮喘的引喘潜伏期，抑制过敏介质组织胺和乙酰胆碱的致喘作用。本研究从临床和动物实验两方面阐述了足三里穴位免疫疗法的作用机理。

英文摘要:

We have studied on preventing and treating anaphylactic asthma with Zusanli(S36)point immunotherapy(ZPIT).Sixty-nine patients were observed.The results showed that the clinical curative effect of ZPIT was not only much higher than that of conventional desensitization therapy,but also the patients’total IgE level was reduced, anti-acarid IgE was lowered,SIgA level was raised,the absolute eosinophilic granulocyte level dropped and pulmonary function recovered.Animal experiment results showed that the ZPIT could more effectively suppress the guinea pigs’anaphylactic asthma allergized by albumin and more obviously resist the guinea pigs’bronchial spasm induced by histamine and acetylcholine than the conventional desensitization therapy and injected normal saline.The immunomodulating action of the ZPIT are elucidated from clinical study and animal experiment in the paper.

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