中药加化疗治疗晚期非小细胞肺癌疗效分析

目的：为探讨中药及化疗在晚期非小细胞肺癌治疗中的价值和规律。方法：对５８例晚期非小细胞肺癌患者给予中药加化疗治疗（中西组），并与２８例单纯化疗（化疗组）及２４例单纯中药治疗（中药组）进行比较。结果：３组近期客观疗效相近，有效率（ＣＲ＋ＰＲ）分别为２２．９％、１３．６％及１３．６％（Ｐ＞０．０５）。中位生存期以中西组最长，为１０．２个月，中药组次之，为８．０个月，化疗组最短，仅５．３个月。远期生存率（Ｋａｐｌａｎ－Ｍｅｉｅｒ法）中西组与中药组相近（Ｐ＞０．０５），均显著高于化疗组（Ｐ＜０．０１，Ｐ＜０．０５）。结论：中医辨证论治对改善晚期非小细胞肺癌患者的中位生存期及远期生存率有益，而化疗在这方面的作用则不明显，且缩小癌灶的能力也十分有限。

英文摘要:

To observe the effect of Chinese medicinal herbs (CMH) and chemotherapy on non small cell imp cancer. Methods: Comparing the therapeutic effects of three treatment regimens on 58 advanced non-small cell imp cancer (NSCLC) patients who were treated with CMH plus chemotherapy (CT), 28 cases treated with CT only, and 24 cases treated with CMH alone. Results: Effective rates (partial remission+complete remission) were 22. 9% in CMH +CT group, 13.6% both in CT and in CMH group. There were no significant differences between these three groups according to the short-term results (P >0. 05). Mean survival time (month) for CMH +CT, CT and CMH grouPS were 10.2, 5.3 and 8.0 respectively. The survival rate (Kaplan Meter method) of both CMH +CT and CMH group were significantly higher than that of CT group(p <0.01, P <0.05) but no significant difference between CMH and CMH+CT group (P>0.05). Conclusion: Chinese medicinal herbs were helpful to improve median survival time and survival rate of patients with advanced NSCLC.

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