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吴耕书,张荔彦,奥田拓道.猪苓多糖对毒激素-L诱导大鼠恶病质样表现的抑制作用[J].中国中西医结合杂志,1997,(4):232-233
猪苓多糖对毒激素-L诱导大鼠恶病质样表现的抑制作用
Inhibitive Effect of Umbellatus Polyporus Polysaccharide on Cachexic Manifestation Induced by toxohormone-L in Rats
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DOI:
中文关键词:  猪苓多糖  毒激素-L  恶病质
英文关键词:Umbellatus polyporus polysaccharide  toxohormone-L  cachexia
基金项目:卫生部科研基金
作者单位
吴耕书  
张荔彦  
奥田拓道  
摘要点击次数: 1166
全文下载次数: 1057
中文摘要:
      目的:探讨肿瘤恶病质的病因及猪苓多糖治疗作用机理。方法:观察猪谷多糖对毒激素-L诱导的恶病质样表现的作用。结果:从人原发性肝癌患者腹水中提取的毒激素-L可在体外显著诱导脂解,体内抑制摄入行为,降低血锌及升高血铜(P<0.01)。结论:毒激素-L与肿瘤恶病质密切相.关,猪苓多糖可抑制毒激素-L在诱导肿瘤恶病质中的作用。
英文摘要:
      To investigate the effect of treatment of cachexia with Umbellatus PolyporusPolysacchsride (UPP). Methods: UPP was used to treat cachexia induced by toxohormone-L. Results: Toxohormone-L from ascites fluid with primary hepetoma could induce lipolysis in vitro significantly, inhibit the intake behsvior, decrease the level of bind zinc, increase that of blood copper (P<0. 01 ), upp could inhibit these effects. Conclusion: Toxohormone-L was closely related withneoplastic cacheds and UPP Could inhabit this effect induced by toxohormone-L significantly.
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