中药快速膀胱超声显像剂的临床及实验研究

目的：为求快速Ｂ超显像并减少副作用。方法：用中药制剂达到快速使膀胱、盆腔在Ｂ超上显像，以便盆腔疾病能得到迅速诊断。通过对１２２例受试者对比观察。临床观察分４组进行：Ⅰ号组（显像剂Ⅰ号，为纯中药制剂）、Ⅱ号组（显像剂Ⅱ号，为中西药复方制剂）、阳性对照组（速尿）及矿泉水对照组。结果：显像剂Ⅰ号既能快速利尿又能减少显像所需的膀胱容量而达到快速显像目的。Ⅰ号组显像时间、膀胱容量均优子速尿组（Ｐ＜０．００１），动物实验参考临床设计进行，结果亦表明显像剂Ⅰ号ｌｈ内的利尿强度明显高于其他各组（Ｐ＜０．０５，Ｐ＜０．０１），而毒性实验表明为无毒级制剂。结论：中药快速膀胱超声显像剂能有效地使膀胱、盆腔快速显像，有助于迅速诊断。

英文摘要:

Objective: To seek for a rapid type B ultrasound developer of Chinese medicinal herbs,so that the bladder and pelvic cavity developed clearly and pelvic cavity diseases could be diagnosed rapidly.Methods: One hundred and twenty-two patients were observed clinically and animal experiments were performed. The rapid bladder ultrasonography developer (RBUD-1, a preparation of Chinese herbal medicine)alone was used in Group 1,composite prescription of Western and Chinese medicine was used in group 2. The control groups were using lasix or mineral water. ResultS: Rapid diuresis and the decrease of the bladder capacity needed for development could be realized by Chinese medical herbs preparation,the difference between Group 1 and control group in developing time and bladder capacity were very significant. Results of animal experiments, which were referred to clinical grouping,showed the diuretic intensity of RBUD-1 within one hour was significantly higher than that in the other groups. Toxicological study showed the RBUD-1 was a non-toxic preparation. Conclusion: RBUD-1 could effectively develop bladder and pelvic cavity,it would help to diagnose in time, on the other hand, it would also contribute for the combination imaging of Chinese and Western medicine.

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