中西医结合人体生理学年龄的临床研究

目的：根据中西医结合理论，探讨衰老程度评估的客观方法。方法：对３８７例４５～６９岁的健康中老年人，分不同等级进行综合测试，测试指标包括中医衰老指征２４项，西医神经生理学５项及实验室生化指标１０项。然后通过逐步回归分析计算，推导中西医结合生理学年龄方程。结果：中西医结合生理学年龄（Ｙ），与相对历法年龄（ｙ）相减（Ｙ－ｙ），求Ｙ－ｙ的平均数及标准差。结果Ｙ－ｙ的平均数为０，标准差为２．２９岁，概括９５％界限为正常值范围。衰老的评估对正常与异常的界限通常只考虑过高的一侧，即历法年龄＋３．７７岁（生理学年龄大于历法年龄３．７７岁者，视为过度衰老）。中医衰老积分与其它多项指标的回归分析证明，血清过氧化脂质、血清铜锌型超氧化物歧化酶等指标和中医衰老积分密切相关。结论：建立中西医结合方程能较客观地反应人的生理学年龄，中医衰老积分的测定有一定的科学性。

英文摘要:

Objective: TCM and western geriatric medical principles were used to study the assessment of aging in mankind. Methods: The authors studied and examined 387 healthy subjects ragging from 45 to 69 years of age. Its indices included 24 TCM senility syndromes, 5 western medical neurophysiological indices. Thereafter, regression analysis was used to deduce a TCM-WM aging formula. Results: Data from all clinical subjects were processed using integrated TCM-WM, physiological age formula to determine the physiological ages(Y) and their corresponding calendar ages (y). The mean values of the age differential of zero, and a standard deviation of 2. 29 years were calculated. From statistical view point, a 95 percentage is an acceptable normal value range. Also, as the objective of the aging assessment only used the higher end of the range. I. E, it is considered there is excessive aging when physiological age is higher than calendar age by 3.37 years. In the process of conducting regression analysis, the authors also discovered that LPO can increase TCM senility syndrome score, whereas CuZnSOD decrease it. Con- clusions:The above clinical study showed that the repression analysis and ace-related TCM indices can comprehensively reflect the natural process of aging in mankind. It also demonstrated the highly predictive nature of TCM senility syndrome score.

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