补肾祛瘀法治疗子宫内膜异位症的临床观察

目的 :探讨补肾祛瘀法治疗子宫内膜异位症的作用机理。方法 :将 1 0 3例子宫内膜异位症患者 ,随机分为内异消治疗组 (5 8例 )和丹哪唑治疗对照组 (45例 )。观察临床症状改善情况、血清内分泌激素FSH、LH、PRL、E2 、P、T的含量、体液免疫和细胞免疫中C3、C4、CD3、CD4、CD8水平以及血浆前列腺素含量测定。结果 :在对痛经症状的纠正和对异常升高的血浆前列腺素的降解方面 ,内异消和丹哪唑无明显差异 (χ2 =0 71 ,P >0 0 5 )。内异消和丹哪唑在不孕的治愈方面有明显差异 (χ2 =1 4 77,P <0 0 1 ) ,而且内异消对内分泌和免疫系统的调节皆有一定作用。结论 :补肾祛瘀法治疗子宫内膜异位症是多效应的 ,不失为临床治疗子宫内膜异位症的有效途径之一。

英文摘要:

Objective: To explore the mechanism of treating endometriosis by tonifying Kidney and removing blood stasis with Neiyixiao Recipe (NYXR). Methods: One hundred and three patients of endometriosis were divided randomly into the NYXR group (58 cases, treated with NYXR) and the control group (45 cases, treated with danazol) and were reviewed for the improvement of clinical symptoms, serum level of FSH, LH, PRL, E 2,P and T, humoral and cellular immunity (C 3,C 4,CD 3,CD 4,CD 8), and plasma prostaglandin after treatment. Results: There was no significant difference in effect between the NYXR group and the control group in relief of dysmenorrhea and degradation of elevated plasma prostaglandin(χ 2=0.71, P>0 05). But there was significant difference between the two groups in curing infertility (χ 2=14 77,P<0 01), and the effect of NYXR in regulating endocrine and immunity was significantly better than that of danazol. Conclusion: By tonifying Kidney and removing blood stasis, NYXR is multi effective and being one of effective methods in clinical practice for treatment of endometriosis.

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