参麦注射液对充血性心力衰竭的疗效观察

作者	单位
柳志红	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
程显声	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
张朝阳	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
赵彦芬	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
何建国	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
张云	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
倪新海	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037
陈白屏	Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al Division of Cardio Pulmonary Circulation Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing (100037

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中文摘要:

目的 :观察参麦注射液对充血性心力衰竭患者的临床疗效。方法 :应用随机交叉对比的方法 ,对 1 6例慢性充血性心力衰竭患者进行参麦注射液和门冬氨酸钾镁治疗比较。结果 :应用参麦注射液 2周后 ,左室射血分数由 2 9 5±9 0升至 3 6 6±1 0 2 (P <0 0 5 ) ,68 75 %的患者心功能改善 ,未发现明显毒副作用 ;门冬氨酸钾镁可使 3 7 5 0 %的患者心功能改善 ,但左室射血分数无明显变化。结论 :参麦注射液是治疗充血性心力衰竭的有效药物。

英文摘要:

Objective: To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure. Methods: Effect of 16 cases treated with SMI or potassium magnesium aspartate was observed by randomized cross over method and compared. Results: By using SMI for 2 weeks, patients’left ventricular ejective fraction (LVEF)could be increased from 29.5±9 0 to 36 6±10 2 (P<0 05), the heart function of 68.75% patients was improved, no side effects or toxicity was observed. Potassium magnesium aspartate could improve heart function in 37.50% patients only but with no effect on LVEF. Conclusion: SMI is an effective and safe therapy in treating patients with congestive heart failure.

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