扶正抗白冲剂对急性白血病患者长期存活影响的临床研究

作者	单位
麻柔	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
刘锋	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
杨经敏	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
马玲	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
许勇钢	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
胡乃平	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
胡晓梅	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
薛向军	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
李柳	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091
王楠	Ma Rou, Liu Feng, Yang Jingmin, et al Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091

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中文摘要:

目的 :研究扶正抗白冲剂对急性白血病患者长期存活的影响 ,探讨扶正中药治疗微小残留白血病的机理。方法 :以扶正抗白冲剂治疗完全缓解期的急性白血病患者 90例 ,观察其对 5年持续缓解率 (EFI)和长期生存率 (OS)的影响 ;检测了用扶正抗白冲剂治疗前后患者免疫功能变化。结果 :90例患者 5年EFI为 64 2 % ,5年OS为 77 2 % ;患者免疫功能明显改善。结论 :扶正抗白冲剂可提高急性白血病患者 5年EFI和 5年长期生存率 ,这种提高可能是通过改善患者免疫功能达到的。

英文摘要:

Objective: To observe the effect of Fuzheng Kangbai Granule (FZKBG) on event free interval (EFI) and over survival (OS)of patients with acute leukemia, and to study the mechanism of FZKBG. Methods: FZKBG was used in 90 cases of completely remitted acute leukemia, immune functions of patients before and after using FZKBG were measured. Results: Five year EFI and OS were 64.2% and 77.2% of 90 cases of completely remitted acute leukemia, and the immune functions after using FZKBG have improved significantly. Conclusions: FZKBG could increase the EFI and OS of patients with acute leukemia, and the improved immune functions may play a role in increasing 5 year EFI and OS.

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