脑卒中患者脂质代谢紊乱与中医辨证分型的关系

作者	单位
赵瑞祥	中国人民解放军空军杭州疗养院!杭州310007
周向东	中国人民解放军空军杭州疗养院!杭州310007
王凤山	中国人民解放军空军杭州疗养院!杭州310007
郭雪云	中国人民解放军空军杭州疗养院!杭州310007

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中文摘要:

目的 :分析脑卒中患者脂质代谢紊乱与中医辨证分型的关系。方法 :脑卒中组1 42例和健康对照组 (对照组 ) 1 0 0例进行血脂、脂蛋白和载脂蛋白水平的测定。按中医辨证将脑卒中患者分 3组 :痰湿阻滞 (PDS)、阴虚阳亢 (YDYH)和气虚血瘀 (QDBS)组。结果 :PDS和QDBS组患者血清总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白 (HDL)、低密度脂蛋白(LDL)、载脂蛋白A1 (apoA1 )、载脂蛋白B(apoB)和apoA1 /apoB等各项指标与对照组比较有显著性差异 (P <0 0 5或 0 0 1 ) ,PDS组脂质代谢紊乱最为严重。YDYH组与对照组相比较 ,除TG、apoA1 /apoB有显著性差异 (P <0 0 5 )外 ,其余各项指标与对照组相比较均无显著性差异(P >0 0 5 )。结论 :脑卒中患者脂质代谢紊乱与中医辨证分型有密切关系。对PDS和QDBS型中风患者除常规治疗外 ,还应给予祛湿化痰和通络化瘀治疗。

英文摘要:

Objective: To analyse the relationship between lipometabolic disorder in stroke with TCM Syndrome Differentiation and Typing. Methods: The serum lipid, lipoprotein and apo lipoprotein level of TCM treated group (142 cases) and control group (100 cases) were determined. The patients were subdivided into three Type groups according to TCM Syndrome Differentiation: Phlegm Dampness Stagnation (PDS), Yin Deficiency with Yang Hyperactivity (YDYH) and Qi Deficiency with Blood Stasis (QDBS) group. Results: The results showed that the level of TC, TG, HDL, LDL, apoA 1, apoB and apoA 1/apoB were significantly different in PDS and QDBS as compared with control group (P<0 05,P<0 01, respectively), while lipometabolic disorder of PDS was most serious in TCM Syndrome Differentiation of stroke. The level of TG, apoA 1/apoB were significantly different in YDYH in comparing with control group (P<0 05). While the level of TC, HDL, LDL and apoB were insignificantly different than those of control group (P>0 05). Conclusions: This study showed that lipometabolic disorder of stroke were correlated with Syndrome Differentiation of TCM. Stroke with PDS and QSBS should give removing Phlegm Dampness, dredging Meridian and removing blood stasis treatment besides routine treatment.

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