熟地多糖联合康力龙治疗慢性再生障碍性贫血34例

作者	单位
元阿萍	Yuan Aping, Liu Chao, Huang Xia, et al The Second Affiliated Hospital of Henan Medical University, Zhengzhou (450003
刘超	Yuan Aping, Liu Chao, Huang Xia, et al The Second Affiliated Hospital of Henan Medical University, Zhengzhou (450003
黄霞	Yuan Aping, Liu Chao, Huang Xia, et al The Second Affiliated Hospital of Henan Medical University, Zhengzhou (450003
王秀菊	Yuan Aping, Liu Chao, Huang Xia, et al The Second Affiliated Hospital of Henan Medical University, Zhengzhou (450003
余学端	Yuan Aping, Liu Chao, Huang Xia, et al The Second Affiliated Hospital of Henan Medical University, Zhengzhou (450003

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中文摘要:

目的 :探讨熟地多糖治疗慢性再生障碍性贫血 (慢性再障 )的疗效及副作用。方法 :用熟地多糖口服液联合康力龙治疗慢性再障 3 4例 ,疗程 3个月 ,同时和 1 7例单用康力龙的病例作对比。结果 :治疗组总有效率为 85 3 % ,对照组为 5 8 8% ,两组比较有显著性差异 (P<0 0 5 )。治疗组症状改善明显较对照组快 ,症状积分两组比较有显著性差异 (P <0 0 1 )。治疗组治疗 3个月后外周血细胞明显升高 ,和治疗前比较有显著性差异 (P <0 0 1 ) ,治疗中未发现熟地多糖有任何毒副作用。结论 :熟地多糖和康力龙联合治疗慢性再障能起到相加作用 ,加速症状的改善 ,提高疗效 ,不增加副作用。

英文摘要:

Objective: To investigate the effect and side effect of prepared Rehmannia polysaccharide (PRP) associated with stanozolol in treating chronic aplastic anemia (CAA). Methods: Thirty four cases of CAA were treated by PRP liquid associated with stanozolol, course of 3 week treatment, and control group (17 cases of CAA) was treated by stanozolol alone. Results: Effective rate was 85.3% in treatment group, and that of control group was 58.8%, there was significant difference between them (P<0 05). Symptom remission of treatment group was earlier than that of control group, symptom scoring between two groups, the difference was highly significant (P<0 01). Blood cell had a distinct elevation after treatment with PRP associated with stanozolol, and had a significant difference in comparing with pre treatment in treatment group (P<0 01). Side effect of PRP was not found during treatment of CAA. Conclusions: PRP associated with stanozolol to treat CAA has an additional effect, it can accelerate symptom remission without any additional side effect.

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