长效止痛剂治疗肛肠病术后疼痛102例

作者	单位
王业皇	南京市中医院!南京210001
李柏年	南京市中医院!南京210001
欧阳强	南京市中医院!南京210001
余苏萍	南京市中医院!南京210001
哈楠林	南京市中医院!南京210001

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中文摘要:

目的 :观察长效止痛剂治疗肛肠病术后疼痛的临床疗效及作用机理。方法 :根据中医理论 ,分析肛肠病术后疼痛的病理特点 ,选择能祛风胜湿、缓急止痛的汉防己为主药 ,从中提取汉防己总碱 ,配伍亚甲蓝及布比卡因 ,制成注射液。临床观察分 3组 ,即长效止痛剂组(1 0 2例 )、常规处理组 (80例 )、曲马多组 (3 0例 ) ,观察其止痛疗效。结果 :长效止痛剂的完全止痛效果达 5 6 86% ,优于单纯布比卡因和曲马多 (P <0 0 5 )。研究表明 ,长效止痛剂具有明显的局部止痛作用 ,同时具有明显的肌肉松弛作用。结论 :长效止痛剂对肛肠疾病术后疼痛具有明显的止痛效果。

英文摘要:

Objective: To observe the clinical effect and experimental result of long acting analgesic in the treatment of anorectal post operational pain. Methods: Analysing the pathological features of anorectal post operational pain, and select the Radix Stephana Tetrandra, which could disperse pathogenic Wind and dampness, relieve spasm and pain, as the major component. The authors extracted Sinomenine from the Stephana and by mixing with methylene blue and bupivacaine hydrochloride, an injection was prepared. Three groups were in the clinical observation: Long acting analgesic group (102 cases), routine treatment group (80 cases) and the control group treated by Tramal (30 cases). The curative effect was observed and animal experiment was conducted. Results: The total analgesic rate of the long acting analgesia was 56.86%. The clinical effect was better than using Bupivacaini hydrochloride or Tramal alone (P<0 05). It was shown in experiment that long acting analgesic had obvious effects of topical analgesic and muscle relaxant. Conclusions: Long acting analgesic has significant effect in relieving the anorectal post operational pain.

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