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储旭华,侯熙德.柴胡及桂枝治疗多发性肌炎的实验研究[J].中国中西医结合杂志,1998,(6):356-358
柴胡及桂枝治疗多发性肌炎的实验研究
Experimental Study on Therapeutical Effect of Chinese Medicine on Polymyositis in Guinea Pigs
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DOI:
中文关键词:  柴胡  桂枝  多发性肌炎
英文关键词:Radix Bupleuri  Ramulus Cinnamomi  polymyositis
基金项目:江苏省教育委员会自然科学基金!(No.95 0 46 - 36 3 FA95 0 1)
作者单位
储旭华 南京医科大学第一附属医院!南京210029 
侯熙德 南京医科大学第一附属医院!南京210029 
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中文摘要:
      目的 :观察柴胡和桂枝治疗多发性肌炎的疗效。方法 :取柯萨奇病毒B1 诱导的多发性肌炎豚鼠模型 40只 ,随机分为 3组 :A组 (1 5只 )给柴胡 ,B组 (1 5只 )给桂枝 ,C组 (1 0只 )作为空白对照 ,比较症状、肌酶谱和病理改变。结果 :A、B两组的症状、肌酶谱和病理改变明显好转 ,C组有加重的表现 (P <0 0 5 )。结论 :柴胡和桂枝对豚鼠多发性肌炎有良好的治疗作用。
英文摘要:
      Objective: To study the therapeutical effects of Radix Bupleuri and Ramulus Cinnamomi on virus polymyositis in guinea pigs. Methods: Forty polymyositis guinea pigs induced by Coxsackievirus B 1 were divided at random into A(n=15), B(n=15), C(n=10) groups. A, B groups were treated with Radix Bupleuri and Ramulus Cinnamomi respectively. C group received no treatment. Sign, muscle enzyme spectrum and pathological changes were compared. Results: A and B groups became better. C group showed an aggravating trend (P<0 05). Conclusion: Radix Bupleuri and Ramulus Cinnamomi had therapeutic effect on polymyositis in guinea pigs.
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